Muva nje, izikhondlakhondla zikagwayi ezimbili ezinkulu, i-PMI ne-BAT, ngokulandelana kwazo zishicilele amaphepha ocwaningo kumajenali ezokwelapha aphezulu emhlabeni jikelele.Imiphumela yocwaningo ibonisa ukuthi imikhiqizo emisha kagwayi efana ne-e-cigarettes nemikhiqizo engashisi ayinabungozi futhi inobuthi kunogwayi wendabuko, futhi inganciphisa kakhulu umthelela ohlelweni lokuphefumula.umonakalo.
Njengoba ukuqwashisa kwabantu ngezingozi zokubhema kukhula, ugwayi we-elekthronikhi uya ngokuya uqashelwa njengokuthatha indawo kagwayi, kodwa imiphumela yesikhathi eside yengxube ye-flavour ye-e-cigarette kanye nentuthu kagwayi kubabhemi kusazobhekwa kabanzi.Muva nje, u-PMI uPhilip Morris International ushicilele umbiko wocwaningo "Ukuhlolwa kobuthi bokuphefumula kwentuthu kagwayi kanye nama-aerosols avela ezixubeni zokunambitheka: isifundo seviki le-5 kumagundane we-A/J" ku-British Journal of Toxicology "Journal of Applied Toxicolog", echaza imininingwane. wezihloko ezihlobene Izinyathelo zocwaningo kanye nemiphumela.
Ocwaningweni, amagundane abesilisa angama-87 kanye namagundane angama-174 angenalutho nakhulelwe abelwa emaqenjini okuhlola ayi-9, futhi ahlolwa emoyeni, entuthuni kagwayi, nama-aerosol e-e-cigarette anezingxube ezintathu ezihlukene zama-flavour, aphezulu, aphakathi, naphansi. .Ukuchayeka kufika emahoreni ayi-6 ngosuku, izinsuku ezi-5 ngeviki, amasonto ama-5 kwalandelwa i-necropsy, isisindo somzimba kanye nokuhlolwa kwe-histopathological.
Imiphumela yokugcina yokuhlola ibonise ukuthi uma kuqhathaniswa nokuchayeka entuthuni kagwayi, amagundane achayeka kuma-aerosol e-e-cigarette anama-flavour kanye nangenawo ayengenazo izinguquko eziphawulekayo ezithweni zokuphefumula, ikhala, kanye nezicubu ze-laryngeal epithelial, ezibonisa ukuthi i-e-cigarettes I-sol ayicasuli kancane. kuzicubu nezitho ezihambisanayo.Imiphumela yokuhlolwa iphinde yafakazela ukuthi, uma kuqhathaniswa nogwayi wendabuko, i-e-cigarettes inganciphisa kakhulu ukuvuvukala kwamaphaphu, kanye nokulimala kwe-epithelium yekhala, umphimbo kanye noqhoqhoqho.
I-BAT British American Tobacco ishicilele iphepha locwaningo elinesihloko esithi "An Experimental Analytical and In Vitro Approach to Bridge between Different Different Tobacco Product Variants" kujenali yesayensi "Yeminikelo Yogwayi Nocwaningo Lwe-Nicotine", futhi yenza ucwaningo ngeTHP (imikhiqizo ye-HNB) Toxicology. ukuhlola.Ocwaningweni, intuthu ye-aerosol kanye nentuthu kagwayi yezinhlobonhlobo ezinhlanu ze-THP kanye ne-THP eyodwa eyisisekelo zisetshenziswe njengendawo yokuhlola, futhi i-cytotoxicity yahlolwa ngokusebenza kwamaseli e-epithelial yamaphaphu omuntu.Imiphumela yabonisa ukuthi konke ukusabela kwe-cytotoxic eqenjini le-THP bekungaphansi ngo-95% kunalezo eziseqenjini lentuthu kagwayi, futhi awukho umehluko obalulekile wobuthi phakathi kwama-THP amahlanu ahlukene kanye ne-THP eyisisekelo.
Ucwaningo luphethe ngokuthi ukuthuthukiswa nokuhlinzekwa kweminye imikhiqizo kagwayi ne-nicotine kukhula ngokushesha, abathengi baya ngokuya bemukela imikhiqizo emisha efana ne-THP, futhi ukuphepha nobungozi bayo njengengxenye yokuhlola okunobuthi kufanele ukunakwa kwemboni.Kuphela uma umkhiqizo ufinyelela amazinga (okuhlanganisa nokusebenza kwebhethri) lapho ungadlala khona kangcono indima yawo enhle njengesu lezempilo lomphakathi.
Izithenjwa:
U-Ee Tsin Wong, uKarsta Luettich, uLydia Cammack, nabanye.Ukuhlolwa kobuthi bokuhogela bentuthu kagwayi nama-aerosol avela ezixubeni zokunambitheka: Ucwaningo lwamaviki angu-5 kumagundane e-A/J.Ijenali ye-toxicolog esetshenzisiwe, 2022
U-Tomasz Jaunky, uDavid Thorne, u-Andrew Baxter, nabanye.Indlela Yokuhlola Yokuhlola kanye Ne-In Vitro Yebhuloho Phakathi Kwezinhlobonhlobo Ezihlukene Zomkhiqizo Kagwayi Oshisayo.Iminikelo Ocwaningweni lukagwayi ne-Nicotine, ngo-2022.
Isikhathi sokuthumela: Feb-01-2023
